Not so many today.
Non-fiction
The Rules of Management, by Richard Templar (2005)
The Rise and Fall of the House of Medici, by Christopher Hibbert (2005)
The Belgian House of Representatives: From Revolution to Federalism, by Derek Blyth, Alistair MacLean, and Rory Watson (2006)
SF
Keepers of the Peace, by Keith Brooke (2005)
The Hallowed Hunt, by Lois McMaster Bujold (2005)
Never Let Me Go, by Kazuo Ishiguro (2006)
A Feast For Crows, by George R.R. Martin (2011)
Dracula, by Bram Stoker (2012)
Comics
The Complete Maus, by Art Spiegelman (2004)
The best
Art Spiegelman’s Maus is a classic invocation of the Holocaust with the humans involved portrayed as anthropomorphic animals. Of many memorable literary treatments of the genocide, this is one of the greatest. (Review; get it here.)
Honourable mentions
Four heavyweight sff classics here, each of which is well worth revisiting – or trying for the first time if you haven’t.
The Hallowed Hunt (review; get it here) and A Feast for Crows (review; get it here) are both worthy installments in well-known fantasy series.
Dracula (review; get it here) and Never Let Me Go (review; get it here) are both stories of bodysnatching with perhaps more thematic similarities than you might have thought.
The one you haven’t heard of
The one to avoid
None of these is sufficiently good-yet-obscure or sufficiently awful to be worth drawing attention to.