Are you a Doctor Who character? Are you concerned about whether you will live to the end of the story, or die a horrible death? Here’s a useful indicator: are you played by Geoffrey Palmer?
From the Heart of Europe
Books, politics, languages and life
I think that the first Lord President of the Council was John Dudley, duke of Northumberland, in the reign of Edward VI, the appointment (effectively by himself) being in 1551 or 1552, IIRC. The office lapsed at the end of the reign and wasn’t revived until James VI and I needed a suitably grand office with non-specific duties to give someone. Dudley’s inspiration, I do not know.